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- RNF43-mediated suppression of WNT signaling in stem cells
- Understanding mutant Axin-mediated tumorigenesis
- Biophysical analysis of FZD function
- Understanding WNT-FZD specificity and signal specification
- Targeting non-canonical WNT/PCP pathway receptors in chronic lymphocytic leukemia
- Dynamic protein interactions in the noncanonical WNT/PCP pathway
- Detection of ligand dependent FZD conformational changes
- Control of complex assembly in the WNT cascade
- Chaperone binding motifs in disordered WNT signalling proteins
- Targeting intrinsically disordered regions in the WNT pathway
- The in vivo tumor suppressor role of the FZD E3 ubiquitin ligases RNF43 & ZNRF3
- Elucidating the role of stem-cell specfic ubiquitin ligases
- QCM-based WNT binding assay to quantitatively profile WNT-receptor interactions
- Development of bicyclic peptides with WNT modulating activity
- Generation and identification of short active peptides against WNT pathway therapeutic targets
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